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Litesizer DLS: Best-in-Class Particle Sizing
Litesizer DLS delivers exceptional particle sizing accuracy with automatic angle selection, eliminating errors and ensuring optimal measurement conditions. Its advanced MAPS technology provides the highest possible peak resolution, while continuous transmittance monitoring detects sedimentation and agglomeration in real time, improving measurement reliability.
Unique to our system, cmPALS and the Omega Cuvette enhance zeta potential accuracy and repeatability by mitigating aging effects and minimizing electrical gradients.
Beyond particle size analysis, Litesizer DLS features fluorescence and polarization filters, enabling precise particle concentration measurements in both MAPS three-angle and single-angle modes, expanding its analytical capabilities.
Key Features
Three Angles, Real-Time Monitoring for Superior Particle Sizing
Litesizer DLS offers three different detection angles, allowing precise measurement of a wide range of samples. With automatic angle selection, it eliminates errors and ensures optimal measurement conditions for every analysis.
The Multi-Angle Particle Sizing (MAPS) mode delivers exceptional resolution, providing advanced analytical precision for even the most challenging samples.
Setting a new industry standard, our continuous transmission monitoring offers real-time feedback on sample behavior, instantly detecting sedimentation and agglomeration during measurement. This unique feature enhances both measurement quality and reliability, making Litesizer DLS the ideal solution for accurate and dependable particle analysis.
Market-Leading Zeta Potential Analysis
Our dynamic light scattering (DLS) instrument sets the standard for zeta potential measurement with its patented cmPALS technique, specifically designed to eliminate reproducibility uncertainties caused by aging effects.
The Omega Cuvette further enhances measurement reliability by minimizing electrical field gradients, ensuring superior reproducibility with a precision of ±3%.
With an industry-leading particle size range for zeta potential measurement—from 1.3 nm to 100 µm—our instrument offers the widest capability available, delivering precise and consistent results across a broad range of applications.
Kalliope: The Benchmark Software for Particle Sizing
Kalliope software is designed for effortless usability, requiring minimal training to get started. Measurements can be completed in just three clicks, streamlining the workflow for maximum efficiency.
With a unique one-page layout, users get an instant overview of input parameters, measurement signals, and results—all at a glance. Predefined standard reports and organized result summaries ensure quick access to key data, while customizable report templates, Excel export options, and advanced analysis tools enable deeper insights.
For industries with strict compliance requirements, Kalliope is fully compliant with 21 CFR Part 11, guaranteeing data integrity and regulatory adherence.
All the Measuring Modes You Need
Expand your analytical capabilities with Litesizer DLS 701’s particle concentration measurement mode, offering calibration-free concentration analysis for up to three distinct size populations within a single sample. This mode supports both monodisperse and polydisperse samples across a wide concentration range, whether using single-angle DLS or MAPS.
For unmatched accuracy, measure the refractive index of solvents at the exact wavelength and temperature of your analysis (European Patent 3 023 770). This ensures maximum precision for particle size and zeta potential measurements. Litesizer DLS 701 and DLS 501 deliver refractive index measurements with an accuracy of ±0.5%.
Additionally, the Litesizer DLS series goes beyond particle sizing by offering molecular mass measurement, further enhancing its versatility in advanced material analysis.
The Most Advanced Filtering Options Available
The Litesizer DLS 701 and 501 are the only dynamic light scattering instruments on the market that provide a unique choice between fluorescence and polarization filters, applicable across all three detection angles.
This exclusive capability enables particle concentration analysis, as well as MAPS three-angle or selected single-angle analysis with applied filters—offering measurement options unavailable in comparable instruments. This makes it possible to conduct specialized analyses, such as the concentration determination of quantum dots, expanding the range of applications beyond conventional particle sizing.
Zeta potential specifications | |||
Measuring principle | Electrophoretic Light Scattering (ELS) / cmPALS | ||
Measuring range | >= +/-1000 mV | ||
Mobility range | 10-11 m²/V.s to 2 x 10-7 m²/V.s | ||
Size range | 1.3 nm to 100 µm (diameter) | ||
Min. sample concentration | 0.1 mg/mL (lysozyme) | ||
Max. sample concentration | 70 %w/v (sample-dependent) | ||
Max. sample conductivity | 200 mS/cm | ||
Min. sample volume | 50 µL (sample-viscosity-dependent) | ||
Accuracy | Better than +/-10 % | ||
Repeatability | +/-3 % | ||
Molecular mass specifications | |||
Measuring principle | Static Light Scattering (SLS) | ||
Measuring range (mass) | 300 Da to 20 MDa | ||
Measuring range (particle size) | Up to 40 nm (diameter) | ||
Measurement angle | 90° | ||
Min. sample concentration | 0.1 mg/mL (lysozyme) | ||
Accuracy | +/-10 % | ||
Repeatability | +/-5 % | ||
Transmittance specifications | |||
Measuring range | 0 % to 100 % | ||
Min. sample volume | 1.5 µL | ||
Accuracy | Better than +/-1 % | ||
Refractive index specifications | |||
Measuring range | 1.28 to 1.50 | ||
Min. sample volume | 1 mL | ||
Accuracy | +/-0.5 % |